Empire Interactive release.
http://www.mobygames.com/game/windows/house-of-the-dead-2
The HOTD2 is SEGA's lightgun-zombie shooter game which brings his own parody (the level of idiotism in the game).
PC version full ISO. For the control, I recommend a lightgun or a mouse
Most usable lightguns:
http://www.play-asia.com/SOap-23-83-9juf-71-1i-49-en-84-j-70-2vss-40-1.html
http://www.play-asia.com/SOap-23-83-9juf-71-1i-49-en-84-j-70-3rqt.html
Onescreen multiplayer options below:
Mouse, keyboard joystick - 2 player
2 EMS Topgun 2 with ACT Labs Troubleshooter - 2 player
HW: P166, 16 MB RAM, SVGA Card, Dsound, Win9x -> Win7 tested.
Install: setup.exe, then run. Adjust compatibility when needs.